Diphenyl Ether → HCID 14994648, compound

HRID 1896522Notes

Reaction equation

HRID 1896522 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[C:2]1/[CH:10]=[CH:11]/C(N=[N+]=[N-])=O.C1([O:23][C:24]2C=CC=CC=2)C=CC=CC=1.[N:30](CCCC)(CCCC)CCCC>CCCCCC>[C:24]1(=[O:23])[C:3]2[C:4]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[S:1][C:2]=2[CH:10]=[CH:11][NH:30]1

Participants

5

Reactant 3

HCID 7583Diphenyl EtherHCID 7622TributylamineHCID 14994647HCID 14994647, compound

Product 1

HCID 14994648HCID 14994648, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Conditions

Temperature
45 °C

Procedure

A suspension of (2E)-3-(1-benzothien-2-yl)acryloyl azide in diphenyl ether (9.2 equiv) and Bu3N (1.1 equiv) was heated to reflux for 1 h. A solution resulted. The mixture was cooled to 40-50° C. Hexane was added; the mixture was stirred for 30 min, filtered, and washed with hexanes to give the title compound as a yellow solid.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 1 h
  3. customA solution resulted
  4. filtrationfiltered
  5. washwashed with hexanes

Sources & evidence

ORD record
ord-cccb7ab49ebc4e1ab9c81d03b5a493ba
Source dataset
uspto-grants-2013_08
Patent number
US08518964B2

Reaction notes

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