反应详情

The title compound was prepared following the procedure described for Example-146 by using 2-((3,5-dichloropyridin-4-yl)amino)-N-(4-fluoro-3-(trifluoromethyl)phenyl)-7,7-dimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide (Example-196, 0.100 g), THF, conc.HCl to afford 0.057 g of the desired product. 1HNMR (DMSO-d6): δ 1.58 (s, 6H), 3.11 (s, 2H), 7.38 (s, 1H), 7.52 (t, J=5.4 Hz, 1H), 7.68 (m, 1H), 8.30 (d, J=10.2 Hz, 1H), 8.59 (s, 2H), 9.90 (s, 1H), 12.00 (br s, 4H).

1. customThe title compound was prepared