反应详情

Treatment of 2-chloro-3-methyl-4-nitrophenol (15.5 g, 82.7 mmol) with sodium hydride (50%, 4.37 g, 91.0 mmol) and n-propyl bromide (11.2 g, 91.0 mmol) in DMF (300 ml) and subsequent workup as described in 1 (a) gave 2-chloro-3-n-propyloxy-6-nitrotoluene (8.50 g), m.p. 42°-3° C.