Bicarbonate Ion → 5-{[4-(2-Azepan-1-yl-ethoxy)-phenyl]-hydroxymethyl}-6-(2,5-difluorophenyl)-naphthalen-2-ol
Reaction equation
[C:46](=[O:47])([OH:48])[O-:49].[CH2:38]([BH-:39]([CH2:40][CH3:41])[CH2:42][CH3:43])[CH3:44].[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[CH:51]([OH:52])([CH3:53])[CH3:54].[CH:55]([Cl:56])([Cl:57])[Cl:58].[Li+:45].[N:1]1([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([C:17](=[O:18])[c:19]3[c:20](-[c:30]4[c:31]([F:37])[cH:32][cH:33][c:34]([F:36])[cH:35]4)[cH:21][cH:22][c:23]4[cH:24][c:25]([OH:29])[cH:26][cH:27][c:28]34)[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[Na+:50]>>[N:1]1([CH2:8][CH2:9][O:10][c:11]2[cH:12][cH:13][c:14]([CH:17]([OH:18])[c:19]3[c:20](-[c:30]4[c:31]([F:37])[cH:32][cH:33][c:34]([F:36])[cH:35]4)[cH:21][cH:22][c:23]4[cH:24][c:25]([OH:29])[cH:26][cH:27][c:28]34)[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-7b74b7eae9eb4aeea186d58241b34960
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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