Allyl iodide → HCID 131719644, compound

HRID 1900831Notes

Reaction equation

HRID 1900831 reaction equation
[OH:1][C:2]1[C:3]2[C:8]([C:9]([CH3:12])=[CH:10][CH:11]=1)=[N:7][C:6](=[O:13])[C:5]([CH3:15])([CH3:14])[CH:4]=2.[CH2:16](I)[CH:17]=[CH2:18].C(=O)([O-])[O-].[K+].[K+]>C(Cl)(Cl)Cl.CCCCCC>[CH2:18]([O:1][C:2]1[C:3]2[C:8]([C:9]([CH3:12])=[CH:10][CH:11]=1)=[N:7][C:6](=[O:13])[C:5]([CH3:15])([CH3:14])[CH:4]=2)[CH:17]=[CH2:16]

Participants

5

Reactant 3

HCID 11166Allyl iodideHCID 11430Potassium CarbonateHCID 137226530HCID 137226530, compound

Product 1

HCID 131719644HCID 131719644, compoundYield 92.6%

Reagents, catalysts & solvents 1

HCID 21585165Chloroform hexaneSolvent

Procedure

Using 5-hydroxy-3,3,8-trimethylcarbostyril (2.0 g, 9.77 mmol), allyl iodide (1.72 g, 10.2 mmol), and potassium carbonate (3 g, 21.7 mmol), the procedure of Reference Example 41 was followed (reaction, post-treatment, and recrystallization from chloroform-n-hexane). 2.2 g of the title compound was obtained as colorless flakes (92.0%).

Sources & evidence

ORD record
ord-2dc742880ae140aab74c7060e22315f5
Source dataset
uspto-grants-1996_11
Patent number
US05576324

Reaction notes

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