Hydrogen Peroxide → HCID 12940617, compound

HRID 1902809Notes

Reaction equation

HRID 1902809 reaction equation
C([O:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:12][CH:11]=1)(=O)C1C=CC=CC=1.ICl.[I-].[K+].[I:27]([O-])(=O)=O.[K+].OO.[OH-].[Na+]>C(O)(=O)C.CO>[I:27][C:20]1[CH:21]=[CH:22][C:17]([O:16][C:13]2[CH:14]=[CH:15][C:10]([OH:9])=[CH:11][CH:12]=2)=[CH:18][CH:19]=1

Participants

9

Reactant 6

HCID 784Hydrogen PeroxideHCID 4875Potassium IodideHCID 14798Sodium HydroxideHCID 24640Iodine chlorideHCID 2683980HCID 2683980, compoundHCID 23665710Potassium Iodate

Product 1

HCID 12940617HCID 12940617, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 887MethanolSolvent

Procedure

In connection with the foregoing Reaction Scheme, p-phenoxyphenyl benzoate of formula VI is either reacted with iodine monochloride in aqueous acetic acid or treated with potassium iodide and an oxidizing agent, for example potassium iodate or hydrogen peroxide, in aqueous methanol, to afford the iodo derivative of formula VII. This iodo derivative is saponified by heating in alkali, for example alcoholic sodium hydroxide, to give p-(p-iodophenoxy)phenol of formula V.

Sources & evidence

ORD record
ord-71b785b8752d4d14bc90a0768b13d650
Source dataset
uspto-grants-1982_12
Patent number
US04365991

Reaction notes

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