Dichloromethane → N-(2-dimethylaminoethyl)-N-(trans-4-methylcyclohexyl)-2-chloro-4-(2-tetrahydropyranyloxy)cinnamamide
Reaction equation
[CH2:58]([Cl:59])[Cl:60].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[CH3:36][N:37]([CH2:38][CH2:39][NH:40][CH:41]1[CH2:42][CH2:43][CH:44]([CH3:47])[CH2:45][CH2:46]1)[CH3:48].[CH3:49][N:50]([CH3:51])[c:52]1[cH:53][cH:54][n:55][cH:56][cH:57]1.[Cl:1][c:2]1[c:3]([CH:4]=[CH:5][C:6](=[O:7])[OH:8])[cH:9][cH:10][c:11]([O:13][CH:14]2[O:15][CH2:16][CH2:17][CH2:18][CH2:19]2)[cH:12]1.[P:20]([Cl:21])([O:22][CH2:23][CH3:24])([O:25][CH2:26][CH3:27])=[O:28]>>[Cl:1][c:2]1[c:3]([CH:4]=[CH:5][C:6](=[O:8])[N:40]([CH2:39][CH2:38][N:37]([CH3:36])[CH3:48])[CH:41]2[CH2:42][CH2:43][CH:44]([CH3:47])[CH2:45][CH2:46]2)[cH:9][cH:10][c:11]([O:13][CH:14]2[O:15][CH2:16][CH2:17][CH2:18][CH2:19]2)[cH:12]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9877b187a54247c89501f17a468cc5d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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