反应详情

温度

0 °C

To a solution of compound 34e (166 mg, 0.39 mmol) in THF (4 mL) was added oxalyl dichloride (43 μL, 0.50 mmol) dropwise at 0° C., followed by the addition of 2 drops of DMF. The resulting mixture was stirred at 0° C. for 3 h, warmed to room temperature, and stirred for 18 h. The solvents were removed under reduced pressure. The resultant residue, compound 34f, was dried under reduced pressure for 2 h and used in the following step without further purification.

1. temperaturewarmed to room temperature
2. stirringstirred for 18 h
3. customThe solvents were removed under reduced pressure
4. dry with materialThe resultant residue, compound 34f, was dried under reduced pressure for 2 h
5. customused in the following step without further purification