反应详情

Hydroxylamine hydrochloride (8.76 g) was dissolved in water (100 mL). To the solution, a solution of sodium acetate (17.8 g) and 3,3-dimethylcyclohexanone (4.55 g) in methanol (20 mL) was added at room temperature, and the mixture was heated to reflux for 1.5 hours. Organic matter was extracted with ethyl acetate and dried over anhydrous sodium sulfate, and the solvent was then distilled off under reduced pressure to obtain a crude product of 3,3-dimethylcyclohexanone oxime.

1. temperaturethe mixture was heated
2. temperatureto reflux for 1.5 hours
3. extractionOrganic matter was extracted with ethyl acetate
4. dry with materialdried over anhydrous sodium sulfate
5. distillationthe solvent was then distilled off under reduced pressure