反应详情

温度

130 °C

Next, a mixed solution of 11.0 g of 1-bromo-7-t-butylpyrene, 5.78 g of 4-methylphenylboronic acid, 18.05 g of tripotassium phosphate, 2.74 g of tetrabutylammonium bromide, 191 mg of palladium acetate and 220 ml of dimethylformamide was heated and stirred under an argon gas stream at 130° C. for 14 hours. The solution was cooled to room temperature and 250 ml of water was poured into the solution, followed by extraction with 250 ml of dichloromethane. The organic layer was washed three times with 250 ml of water, dried over magnesium sulfate and then evaporated. The concentrate was purified by silica gel column chromatography and then vacuum-dried to obtain 7.63 g of 7-t-butyl-1-(4-methylphenyl)pyrene.

1. temperatureThe solution was cooled to room temperature
2. extractionfollowed by extraction with 250 ml of dichloromethane
3. washThe organic layer was washed three times with 250 ml of water
4. dry with materialdried over magnesium sulfate
5. customevaporated
6. customThe concentrate was purified by silica gel column chromatography
7. customvacuum-dried