Tetrahydrofuran → HCID 59295479, compound

HRID 191575Notes

Reaction equation

HRID 191575 reaction equation
[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[CH:24]([N:25]([CH2:26][CH3:27])[CH:28]([CH3:29])[CH3:30])([CH3:31])[CH3:32].[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([O:10][CH2:11][c:12]2[c:13]([CH3:23])[n:14][c:15]([CH:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[s:16]2)[cH:9]1.[F:33][C:34]([CH2:35][O:36][S:37]([C:38]([F:39])([F:40])[F:41])(=[O:42])=[O:43])([F:44])[F:45].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[Cl:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][c:8]([O:10][CH2:11][c:12]2[c:13]([CH3:23])[n:14][c:15]([CH:17]3[CH2:18][CH2:19][N:20]([CH2:35][C:34]([F:33])([F:44])[F:45])[CH2:21][CH2:22]3)[s:16]2)[cH:9]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 803662,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 81531DiisopropylethylamineHCID 59295393HCID 59295393, compound

Product 1

HCID 59295479HCID 59295479, compound

Sources & evidence

ORD record
ord-5471ec4bcddc4e5e8bce3719901aa74c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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