HRID1918215

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1c(NC(=O)c2cc3ccccc3o2)csc1-c1cnc(OC)cn1

HCID67052227

未命名化合物

PRODUCTS

生成物

结构：COc1cnc(-c2scc(NC(=O)c3cc4ccccc4o3)c2C(=O)O)cn1

HCID67052363

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

溶剂HCID21892291

未命名化合物

PROCEDURE

实验过程

The ester 161 and lithium hydroxide in tetrahydrofuran: methanol:water (3:2:1) is stirred at room temperature for 4 h. The mixture is diluted with DMF and purified by HPLC to provide 162.

WORKUP

后处理

custompurified by HPLC