HRID1918219

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)c1c(NC(=O)c2ccc(C)cc2)csc1-c1ccc(C)cc1

HCID67052278

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(C(=O)Nc2csc(-c3ccc(C)cc3)c2C(=O)O)cc1

HCID67052426

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

溶剂HCID21892291

未命名化合物

PROCEDURE

实验过程

The ester 180 and lithium hydroxide in tetrahydrofuran: methanol:water (3:2:1) is stirred at room temperature for 4 h. The mixture is diluted with DMF and purified by HPLC to provide 181.

WORKUP

后处理

custompurified by HPLC