Allylamine → HCID 70171983, compound

HRID 1935667Notes

Reaction equation

HRID 1935667 reaction equation
[CH2:1]([NH2:4])[CH:2]=[CH2:3].C(N(CC)CC)C.Cl[C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14]>C1(C)C=CC=CC=1>[CH2:16]([O:15][C:13]([CH:3]=[CH:2][CH2:1][NH2:4])=[O:14])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7853AllylamineHCID 8471TriethylamineHCID 10387Benzyl chloroformate

Product 1

HCID 70171983HCID 70171983, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

10.4 ml of allylamine and 19 ml of triethylamine are dissolved in 50 ml of absolute toluene. A 50% solution of benzyl chloroformate in toluene (46.8 ml) is added dropwise to the solution, which has been cooled in an icebath, while stirring. The mixture is stirred at room temperature for a further 1 hour in order to complete the reaction. A precipitate which has formed is filtered off. After that, the filtrate is concentrated and dried to constant weight under high vacuum (70° C., 0.5 mbar).

Workup

  1. temperaturehas been cooled in an icebath
  2. stirringThe mixture is stirred at room temperature for a further 1 hour in order
  3. customthe reaction
  4. customA precipitate which has formed
  5. filtrationis filtered off
  6. concentrationAfter that, the filtrate is concentrated
  7. customdried to constant weight under high vacuum (70° C., 0.5 mbar)

Sources & evidence

ORD record
ord-049349eacbe14a119217dbc64b947513
Source dataset
uspto-grants-2002_05
Patent number
US06388061B1

Reaction notes

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