Nitrogen → HCID 22858538, compound

HRID 1939849Notes

Reaction equation

HRID 1939849 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][NH2:5].O.[O:7]=[CH:8][C@@H:9]([C@H:11]([C@@H:13]([C@@H:15]([CH2:17][OH:18])[OH:16])[OH:14])[OH:12])O.N#N>>[CH3:1][O:2][CH2:3][CH2:4][NH:5][CH:17]1[O:18][C@H:9]([CH2:8][OH:7])[C@@H:11]([OH:12])[C@H:13]([OH:14])[C@H:15]1[OH:16]

Participants

5

Reactant 4

HCID 947NitrogenHCID 962Water2×HCID 80182-Methoxyethylamine2×HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal2×

Product 1

HCID 22858538HCID 22858538, compound

Procedure

N-(2-methoxyethyl)-glucosylamine (sugar adduct) is prepared starting with 1728.26 g of 50 wt.% 2-methoxyethylamine in water (11.5 moles, 1.1 mole equivalent of 2-methoxyethylamine) placed under an N2 blanket at 10° C. 2768.57 grams of 50 wt. % glucose in water (10.46 moles, 1 mole equivalent of glucose), which is degassed with N2, is added slowly, with mixing, to the methoxyethylamine solution keeping the temperature below 10° C. The solution is mixed for about 40 minutes after glucose addition is complete. It can be used immediately or stored 0° C.-5° C. for several days.

Workup

  1. customat 10° C
  2. additionis added slowly
  3. customthe temperature below 10° C
  4. additionThe solution is mixed for about 40 minutes
  5. waitstored 0° C.-5° C. for several days

Sources & evidence

ORD record
ord-0499130b16a24f38a0446870bca3dce8
Source dataset
uspto-grants-1997_12
Patent number
US05698046

Reaction notes

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