反应详情

0.800 g of N,N-diethyl-2-(3-formyl-1H-indol-1-yl)acetamide was solubilized in 4.2 ml of isopropanol. 0.238 g of piperidine was added, followed by 0.435 g of 2,3-dihydro-1H-indolizinium chloride dissolved in 7 ml of isopropanol. The reaction mixtures were brought to 80° C. for 24 h, with stirring. 50 ml of ethyl acetate were added in order to precipitate the dye. The precipitate was filtered off, and washed with 3 times with 25 ml of ethyl acetate before being dried under vacuum until a constant weight was obtained. 1.09 g of orange powder were recovered. The analyses were in conformity with the expected structure.

1. customThe reaction mixtures
2. customto precipitate the dye
3. filtrationThe precipitate was filtered off
4. washwashed with 3 times with 25 ml of ethyl acetate
5. custombefore being dried under vacuum until a constant weight
6. customwas obtained
7. custom1.09 g of orange powder were recovered