HRID194495

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6809

Phthalimide

C8H5NO2

HCID8028

Tetrahydrofuran

C4H8O

HCID11776

Triphenylphosphine

C18H15P

HCID220568

Diethyl azodicarboxylate

C6H10N2O4

HCID2784733

(5-bromopyridin-3-yl)methanol

C6H6BrNO

PRODUCTS

生成物

HCID22992261

2-[(5-Bromopyridin-3-yl)methyl]-1H-isoindole-1,3(2H)-dione

C14H9BrN2O2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7c99b8419d9d4bb0b03bf4e63a7cc69f
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应 SMILES

[Br:31][c:32]1[cH:33][n:34][cH:35][c:36]([CH2:38][OH:39])[cH:37]1.[CH2:52]1[O:53][CH2:54][CH2:55][CH2:56]1.[O:20]=[C:21]1[NH:22][C:23](=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]21.[O:40]=[C:41]([O:42][CH2:43][CH3:44])[N:45]=[N:46][C:47]([O:48][CH2:49][CH3:50])=[O:51].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:20]=[C:21]1[N:22]([CH2:38][c:36]2[cH:35][n:34][cH:33][c:32]([Br:31])[cH:37]2)[C:23](=[O:24])[c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]21