反应详情

Benzyl bromide (21.4 ml) was added to a stirred mixture of 2-bromo-4-trifluoromethylphenol (46.4 g) and potassium carbonate (39 g) in DMF (200 ml). After 18 h, the mixture was partitioned between diethylether and water, the organic layer washed with water, 2M sodium hydroxide solution, water, dried and the solvent evaporated under reduced pressure. Yield 58.7 g

1. customthe mixture was partitioned between diethylether and water
2. washthe organic layer washed with water, 2M sodium hydroxide solution, water
3. customdried
4. customthe solvent evaporated under reduced pressure