Hydrochloric Acid → HCID 88176610, compound

HRID 1952801Notes

Reaction equation

HRID 1952801 reaction equation
[ClH:1].C(OCC)(=O)C.[N:8]1([CH2:13][CH2:14][CH2:15][NH:16][C:17]([O:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])[CH:28]=[O:29])=[O:18])[CH:12]=[CH:11][N:10]=[CH:9]1>C(O)C>[ClH:1].[N:8]1([CH2:13][CH2:14][CH2:15][NH:16][C:17]([O:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47])[CH:28]=[O:29])=[O:18])[CH:12]=[CH:11][N:10]=[CH:9]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 54068388HCID 54068388, compound

Product 1

HCID 88176610HCID 88176610, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4N Hydrochloric acid--ethyl acetate solution (0.10 ml) was added to a solution of [2-[[N-[3-(1-imidazolyl)propyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide (0.200 g) in ethanol (2 ml) at room temperature. After being stirred for 20 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 0.201 g of the aimed compound as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-6f2cba8d948e4aeea1e75f0f6945929f
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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