Hydrochloric Acid → HCID 88177255, compound

HRID 1952807Notes

Reaction equation

HRID 1952807 reaction equation
[ClH:1].[CH2:2]([N:4]([CH2:39][CH3:40])[CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[N:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH:19]=[O:20])=[O:9])[CH3:3]>C(OCC)(=O)C>[ClH:1].[CH2:39]([N:4]([CH2:2][CH3:3])[CH2:5][CH2:6][NH:7][C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[N:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH:19]=[O:20])=[O:9])[CH3:40]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54102642HCID 54102642, compound

Product 1

HCID 88177255HCID 88177255, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (0.20 ml) was added to a solution of [2-[[N-[2-(diethylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide (0.42 g) in ethyl acetate (5 ml) at room temperature. After being stirred for 15 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 0.35 g of the aimed compound as white crystals.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-7a3f3b1f031d4c9a9105c1b1ea9075f7
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

Loading…