Hydrochloric Acid → HCID 70304038, compound

HRID 1952818Notes

Reaction equation

HRID 1952818 reaction equation
[ClH:1].[CH2:2]([NH:20][C:21](=[O:40])[CH2:22][C:23]1[CH:39]=[CH:38][CH:37]=[CH:36][C:24]=1[CH2:25][CH:26]1[CH2:31][N:30]([CH3:32])[CH2:29][CH2:28][N:27]1[C:33]([O-:35])=[O:34])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>C(OCC)(=O)C>[ClH:1].[CH2:2]([NH:20][C:21](=[O:40])[CH2:22][C:23]1[CH:39]=[CH:38][CH:37]=[CH:36][C:24]=1[CH2:25][CH:26]1[CH2:31][N:30]([CH3:32])[CH2:29][CH2:28][N:27]1[C:33]([OH:35])=[O:34])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86755726HCID 86755726, compound

Product 1

HCID 70304038HCID 70304038, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

4N Hydrochloric acid--ethyl acetate solution (1.44 ml) was added to a solution of 2-[2-(octadecylamino)-2-oxoethyl]benzyl-4methyl-1-piperazinecarboxylate (2.60 g) in ethyl acetate (39 ml) at room temperature. After being stirred for 30 minutes, the reaction mixture was concentrated. The residue was recrystallized from ethyl acetate-ethanol mixed solvent, thereby yielding 2.42 g of the aimed compound as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized from ethyl acetate-ethanol mixed solvent

Sources & evidence

ORD record
ord-0f0f600f37504d68ac42f1a02b05cff1
Source dataset
uspto-grants-2000_09
Patent number
US06114325

Reaction notes

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