Hydrochloric Acid → HCID 23301836, compound

HRID 1953016Notes

Reaction equation

HRID 1953016 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]2[CH2:14][CH2:13][NH:12][C:11]2=[O:15])=[CH:5][CH:4]=1)#[N:2].[ClH:16]>[Pd].O1CCCC1>[ClH:16].[O:15]=[C:11]1[NH:12][CH2:13][CH2:14][N:10]1[CH2:9][C:6]1[CH:7]=[CH:8][C:3]([CH2:1][NH2:2])=[CH:4][CH:5]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 23301864HCID 23301864, compound

Product 1

HCID 23301836HCID 23301836, compoundYield 81%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to Example 43b) from 1-[(4-cyanophenyl)methyl]imidazolidin-2-one by catalytic hydrogenation using palladium/activated charcoal and in the presence of 1 equivalent of 1N hydrochloric acid in a yield of 81% of theory. Colourless crystals, Mp. >250° C. (Tetrahydrofuran).

Sources & evidence

ORD record
ord-b6b34851cb80465d9c11a09952966d19
Source dataset
uspto-grants-2000_09
Patent number
US06114390

Reaction notes

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