反应详情

The benzyl trifluoroacetate 8 (17.9 g) was dissolved in dry THF, and dry lithium bromide (5.06 g) was added with stirring. The mixture was refluxed overnight, cooled, diluted with acetonitrile, and extracted three times with hexane. The hexane layers were combined, dried, filtered, and concentrated, thereby leaving the product 10 as a white oil in 88% yield.

1. temperatureThe mixture was refluxed overnight
2. temperaturecooled
3. extractionextracted three times with hexane
4. customdried
5. filtrationfiltered
6. concentrationconcentrated