3-Pyridinecarboxaldehyde → HCID 54560653, compound

HRID 1957355Notes

Reaction equation

HRID 1957355 reaction equation
[NH2:1][N:2]1[CH:6]=[N:5][NH:4][C:3]1=[O:7].[N:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]=O)[CH:9]=1>Cl>[N:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]=[N:1][N:2]2[CH:6]=[N:5][NH:4][C:3]2=[O:7])[CH:9]=1

Participants

4

Reactant 2

HCID 103713-PyridinecarboxaldehydeHCID 5676244-amino-4,5-dihydro-1H-1,2,4-triazol-5-one

Product 1

HCID 54560653HCID 54560653, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidCatalyst

Procedure

A mixture of 4 g of 4-amino-1,2,4-triazol-3-one and 100 ml of alcohol is heated to the reflux temperature and 4.3 g of pyridine-3-carbaldehyde and 2 drops of 6N hydrochloric acid are added thereto. After 30 minutes under reflux the reaction mixture is cooled to 20°. The product that has precipitated is then filtered off with suction and dried under a high vacuum. 4.6 g of the title compound having a melting point of 264°-265° are obtained.

Workup

  1. additionare added
  2. temperatureAfter 30 minutes under reflux the reaction mixture
  3. temperatureis cooled to 20°
  4. customThe product that has precipitated
  5. filtrationis then filtered off with suction
  6. customdried under a high vacuum
  7. customare obtained

Sources & evidence

ORD record
ord-dc30621c02424c168035bbb5f4125e6f
Source dataset
uspto-grants-1998_07
Patent number
US05783704

Reaction notes

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