HRID195825

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID787

Hydroxylamine

H3NO

HCID6956

Phthalamide

C8H8N2O2

HCID8028

Tetrahydrofuran

C4H8O

HCID11776

Triphenylphosphine

C18H15P

结构：O=C(NC(CCO)c1ccccc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1

HCID10311041

3-([1,1'-biphenyl]-4-ylsulfonyl)-N-(3-hydroxy-1-phenylpropyl)-1,3-thiazolidine-2-carboxamide

C25H26N2O4S2

PRODUCTS

生成物

结构：O=C(NC(CCN1C(=O)c2ccccc2C1=O)c1ccccc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1

HCID68622063

3-([1,1'-biphenyl]-4-ylsulfonyl)-N-[3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-phenylpropyl]-1,3-thiazolidine-2-carboxamide

C33H29N3O5S2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0173e7040b954371aa3b1d22c7e8f4a8
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (6/10)

反应 SMILES

[CH2:67]1[O:68][CH2:69][CH2:70][CH2:71]1.[NH2:1][OH:2].[NH2:36][C:37](=[O:38])[c:39]1[cH:40][cH:41][cH:42][cH:43][c:44]1[C:45]([NH2:46])=[O:47].[c:3]1(-[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[N:12]2[CH:13]([C:17](=[O:18])[NH:19][CH:20]([CH2:21][CH2:22][OH:23])[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[S:14][CH2:15][CH2:16]2)[cH:7][cH:8]1.[c:48]1([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[cH:62][cH:63][cH:64][cH:65][cH:66]1>>[c:3]1(-[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[N:12]2[CH:13]([C:17](=[O:18])[NH:19][CH:20]([CH2:21][CH2:22][N:46]3[C:37](=[O:38])[c:39]4[cH:40][cH:41][cH:42][cH:43][c:44]4[C:45]3=[O:47])[c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[S:14][CH2:15][CH2:16]2)[cH:7][cH:8]1