Hydrochloric Acid → 1-Isopropyl-4-(1-(4-fluorophenyl)-2-{4-[4-(2-methoxynaphthalen-1-yl)butyl]piperazin-1-yl}-2-oxoethyl)piperidine
Reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[ClH:1].[F:2][c:3]1[cH:4][cH:5][c:6]([CH:9]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][c:22]3[c:23]([O:32][CH3:33])[cH:24][cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[CH2:16][CH2:17]2)[CH:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[cH:7][cH:8]1.[I:46][CH:47]([CH3:48])[CH3:49].[K+:44].[K+:45]>>[F:2][c:3]1[cH:4][cH:5][c:6]([CH:9]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][CH2:20][CH2:21][c:22]3[c:23]([O:32][CH3:33])[cH:24][cH:25][c:26]4[cH:27][cH:28][cH:29][cH:30][c:31]34)[CH2:16][CH2:17]2)[CH:34]2[CH2:35][CH2:36][N:37]([CH:47]([CH3:48])[CH3:49])[CH2:38][CH2:39]2)[cH:7][cH:8]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-38b65f9000814fc3aa355272c38cf6d1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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