Hydrochloric Acid → HCID 20400419, compound

HRID 1981243Notes

Reaction equation

HRID 1981243 reaction equation
C(O[C:5]1[C:19]([O:20]C(=O)C)=[C:18]([O:24]C(=O)C)[CH:17]=[CH:16][C:6]=1[C:7]([CH:9]([C:13](=[O:15])[CH3:14])[C:10]([O-:12])=[O:11])=[O:8])(=O)C.Cl>O1CCCC1>[OH:24][C:18]1[C:19]([OH:20])=[C:5]2[C:6]([C:7](=[O:8])[C:9]([C:10]([OH:12])=[O:11])=[C:13]([CH3:14])[O:15]2)=[CH:16][CH:17]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 20400417HCID 20400417, compound

Product 1

HCID 20400419HCID 20400419, compoundYield 47.2%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
70 °C

Procedure

The thus-obtained 2-(2,3,4-triacetoxybenzoyl)-3-oxobutanoate (3.2 g) was taken up in a mixture of tetrahydrofuran (160 ml) and 3N-HCl (160 ml) and agitated at 70° C. for 20.5 hours. The reaction mixture was concentrated to 20 ml and the resulting precipitate was collected by filtration. It was washed with water and then dried to give the desired product (0.94 g).

Workup

  1. concentrationThe reaction mixture was concentrated to 20 ml
  2. filtrationthe resulting precipitate was collected by filtration
  3. washIt was washed with water
  4. customdried

Sources & evidence

ORD record
ord-49e7b194d8d4469d8c5ef0d5eefe27c3
Source dataset
uspto-grants-1985_04
Patent number
US04513145

Reaction notes

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