反应详情

温度

5 °C

In a 1 liter 3-necked flask were combined 400 ml dry THF and 40 ml distilled n-butylamine (0.405 mol). After cooling to 5° C. in an ice bath, 20 ml (0.205 mol) methacryloyl chloride was added slowly so as to keep the temperature below 10° C. The precipitate was removed by filtration, and the filtrate concentrated on a rotary evaporator. 1 g DNPD was added and the oil distilled at 76°-78° C. and 20 m torr. Yield 24.3 g (84%).

1. customIn a 1 liter 3-necked flask were combined
2. customthe temperature below 10° C
3. customThe precipitate was removed by filtration
4. concentrationthe filtrate concentrated on a rotary evaporator
5. addition1 g DNPD was added
6. distillationthe oil distilled at 76°-78° C.