Dimethylformamide → 3-[2-Benzyl-6-(2-ethoxyethyl)oxy-3-pyridyl]ethynyl-3-quinuclidinol
Reaction equation
[C:26](#[CH:27])[C:28]1([OH:36])[CH2:29][N:30]2[CH2:31][CH2:32][CH:33]1[CH2:34][CH2:35]2.[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[c:13]1[n:14][c:15]([O:20][CH2:21][CH2:22][O:23][CH2:24][CH3:25])[cH:16][cH:17][c:18]1[Br:19].[CH3:115][CH2:116][O:117][C:118](=[O:119])[CH3:120].[CH3:121][CH2:122][N:123]([CH2:124][CH3:125])[CH2:126][CH3:127].[CH3:1][N:2]([CH3:3])[CH:4]=[O:5].[I-:37].[cH:38]1[cH:39][cH:40][c:41]([P:42]([Pd:43]([P:44]([c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([P:63]([c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[P:82]([c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)([c:89]2[cH:90][cH:91][cH:92][cH:93][cH:94]2)[c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[cH:113][cH:114]1>>[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[c:13]1[n:14][c:15]([O:20][CH2:21][CH2:22][O:23][CH2:24][CH3:25])[cH:16][cH:17][c:18]1[C:27]#[C:26][C:28]1([OH:36])[CH2:29][N:30]2[CH2:31][CH2:32][CH:33]1[CH2:34][CH2:35]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e1ff130c22ac456388da1142437e7c2a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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