Dimethylcarbamoyl Chloride → 5-[6-(3,3-Dimethyl-ureidomethyl)-pyrimidin-4-yloxy]-indole-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:37][N:38]([C:39](=[O:40])[Cl:41])[CH3:42].[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[n:12]2[cH:13][cH:14][c:15]3[cH:16][c:17]([O:21][c:22]4[n:23][cH:24][n:25][c:26]([CH2:28][NH2:29])[cH:27]4)[cH:18][cH:19][c:20]23)[cH:6][cH:7][cH:8]1)([F:30])[F:31]>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[n:12]2[cH:13][cH:14][c:15]3[cH:16][c:17]([O:21][c:22]4[n:23][cH:24][n:25][c:26]([CH2:28][NH:29][C:39]([N:38]([CH3:37])[CH3:42])=[O:40])[cH:27]4)[cH:18][cH:19][c:20]23)[cH:6][cH:7][cH:8]1)([F:30])[F:31]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-63479a6f159849a89c7413dd2cd0e175
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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