proline dl-form → 4-(5-Azido-isoquinoline-6-yloxy)-piperidin-1-carboxylic acid tert-butyl ester
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][CH:25]([O:28][c:29]2[c:30]([I:39])[c:31]3[cH:32][cH:33][n:34][cH:35][c:36]3[cH:37][cH:38]2)[CH2:26][CH2:27]1.[CH3:40][S:41]([CH3:42])=[O:43].[Cu:44][I:45].[N-:11]=[N+:12]=[N-:13].[Na+:14].[Na+:2].[OH-:1].[OH2:46].[OH:3][C:4]([CH:5]1[NH:6][CH2:7][CH2:8][CH2:9]1)=[O:10]>>[N:11](=[N+:12]=[N-:13])[c:30]1[c:29]([O:28][CH:25]2[CH2:24][CH2:23][N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:27][CH2:26]2)[cH:38][cH:37][c:36]2[c:31]1[cH:32][cH:33][n:34][cH:35]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-180cef27fa75428cbc95c79ad6889937
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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