Ethylvanillin → HCID 86607629, compound

HRID 1990812Notes

Reaction equation

HRID 1990812 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1O)[CH:7]=[O:8])[CH3:2].[CH:13]1(Br)[CH2:15][CH2:14]1.C([O-])([O-])=[O:18].[K+].[K+]>CN(C=O)C>[CH:13]1([O:18][C:5]2[C:4]([O:3][CH2:1][CH3:2])=[CH:11][CH:10]=[CH:9][C:6]=2[CH:7]=[O:8])[CH2:15][CH2:14]1

Participants

5

Reactant 3

HCID 8467EthylvanillinHCID 11430Potassium CarbonateHCID 78037Bromocyclopropane

Product 1

HCID 86607629HCID 86607629, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The title compound was prepared analogously to intermediate 2 (4-methoxy-3-propoxy-benzaldehyde) by reaction of 3-ethoxy-4-hydroxy-benzaldehyde with cyclopropyl bromide in DMF using K2CO3 as base. MS (ISP): 206.9 [M+H]+.

Sources & evidence

ORD record
ord-97ddb85d875840c092fd9fd412abfdcf
Source dataset
uspto-grants-2010_01
Patent number
US07645753B2

Reaction notes

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