Dimethylformamide → 3,5-Diethoxybenzaldehyde

HRID 1990841Notes

Reaction equation

O[C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([OH:10])[CH:9]=1)[CH:5]=[O:6].[CH2:11](I)[CH3:12].[C:14]([O-:17])([O-])=O.[K+].[K+].[CH3:20]N(C=O)C>>[CH2:11]([O:10][C:8]1[CH:7]=[C:4]([CH:3]=[C:2]([O:17][CH2:14][CH3:20])[CH:9]=1)[CH:5]=[O:6])[CH3:12]

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6340Iodoethane

HCID 11430Potassium Carbonate

HCID 943653,5-Dihydroxybenzaldehyde

Product 1

HCID 226086163,5-Diethoxybenzaldehyde

Procedure

The title compound was prepared analogously to intermediate 2 (4-methoxy-3-propoxy-benzaldehyde) by reaction of 3,5-dihydroxybenzaldehyde with ethyl iodide in DMF using K2CO3 as base.

Sources & evidence

ORD record: ord-73248d46dfd54785a16705b7421259ac
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645753B2

Reaction notes

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