Dimethylformamide → HCID 59128274, compound

HRID 1990850Notes

Reaction equation

[Cl:1][C:2]1[C:9]([OH:10])=[CH:8][C:7](O)=[CH:6][C:3]=1[CH:4]=[O:5].I[CH2:13][CH3:14].[C:15]([O-:18])([O-])=O.[K+].[K+].[CH3:21]N(C=O)C>>[Cl:1][C:2]1[C:9]([O:10][CH2:13][CH3:14])=[CH:8][C:7]([O:18][CH2:15][CH3:21])=[CH:6][C:3]=1[CH:4]=[O:5]

Participants

Reactant 4

HCID 6228Dimethylformamide

HCID 6340Iodoethane

HCID 11430Potassium Carbonate

HCID 86607633HCID 86607633, compound

Product 1

HCID 59128274HCID 59128274, compound

Procedure

The title compound was prepared analogously to intermediate 2 (4-methoxy-3-propoxy-benzaldehyde) by reaction of 2-chloro-3,5-dihydroxy benzaldehyde with iodoethane in DMF using K2CO3 as base. MS (ISP): 229.3 [M+H]+.

Sources & evidence

ORD record: ord-861906ac03734335a52a87fe3f2f9dc2
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645753B2

Reaction notes

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