Dimethylformamide → N-(2-ethylsulfonylethyl)-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-[1-[4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]quinazolin-2-yl]ethyl]acetamide
Reaction equation
[CH2:27]([CH3:28])[S:29](=[O:30])(=[O:31])[CH2:32][CH2:33][NH:34][CH:35]([CH3:36])[c:37]1[n:38][c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]2[c:45](=[O:59])[n:46]1-[c:47]1[cH:48][cH:49][c:50]([O:53][CH2:54][C:55]([F:56])([F:57])[F:58])[cH:51][cH:52]1.[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[CH3:60][CH2:61][N:62]([CH2:63][CH3:64])[CH2:65][CH3:66].[Cl:16][C:17]([C:18]([Cl:19])=[O:20])=[O:21].[Cl:67][CH2:68][Cl:69].[F:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([CH2:8][C:9](=[O:10])[OH:11])[cH:6][cH:7]1>>[F:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([CH2:8][C:9](=[O:11])[N:34]([CH2:33][CH2:32][S:29]([CH2:27][CH3:28])(=[O:30])=[O:31])[CH:35]([CH3:36])[c:37]2[n:38][c:39]3[cH:40][cH:41][cH:42][cH:43][c:44]3[c:45](=[O:59])[n:46]2-[c:47]2[cH:48][cH:49][c:50]([O:53][CH2:54][C:55]([F:56])([F:57])[F:58])[cH:51][cH:52]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fe5e30120d3c486e940a3eeac7f74848
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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