反应详情

20 g (0.078 mol) of 7-benzyl-3-methylxanthine were stirred at 80° C. for 6 hours with 8.8 g (0.094 mol) of ethoxymethyl chloride and 13 g of potassium carbonate in 500 ml of absolute dimethylformamide, the mixture was filtered and concentrated, and the residue which remained was chromatographed (eluent: dichloromethane/methanol 20:1).

1. filtrationthe mixture was filtered
2. concentrationconcentrated
3. customthe residue which remained was chromatographed (eluent: dichloromethane/methanol 20:1)