4-(4,6-Dichloropyrimidin-2-yl)morpholine → HCID 178452014, compound
Reaction equation
Clc1[n:6][c:5]([N:7]2[CH2:12][CH2:11][O:10][CH2:9][CH2:8]2)[n:4][c:2]([Cl:3])[cH:1]1.[CH3:13][C:14]([O:17][C:18]([N:20]1[CH2:28][C:23]2([NH:27][C:26](=O)[O:25][CH2:24]2)[CH2:22][CH2:21]1)=[O:19])([CH3:16])[CH3:15]>>[CH3:13][C:14]([O:17][C:18]([N:20]1[CH2:28][C:23]([NH:27][c:26]2[n:6][c:5]([N:7]3[CH2:12][CH2:11][O:10][CH2:9][CH2:8]3)[n:4][c:2]([Cl:3])[cH:1]2)([CH2:24][OH:25])[CH2:22][CH2:21]1)=[O:19])([CH3:16])[CH3:15]Participants
6
Conditions
- Temperature
- 130 °C
Sources & evidence
- ORD record
- ord-8825f3367cfb465e93457bd2d7d7b860
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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