3-Cyanophenylboronic acid → 3-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
Reaction equation
OB([c:1]1[cH:6][c:5]([C:7]#[N:8])[cH:4][cH:3][cH:2]1)O.[Cl:9][c:10]1[c:18]([c:14]2[n:13][cH:12][n:11]1)[c:17](I)[cH:16][nH:15]2>>[Cl:9][c:10]1[c:18]([c:14]2[n:13][cH:12][n:11]1)[c:17]([c:1]3[cH:6][c:5]([C:7]#[N:8])[cH:4][cH:3][cH:2]3)[cH:16][nH:15]2Participants
9
Reactant 2
Product 1
Reagents, catalysts & solvents 6
Conditions
- Temperature
- 50 °C
Sources & evidence
- ORD record
- ord-4fbc4c6fd42e4267b63143870e63b3c6
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
Loading…