Potassium cyclopropyltrifluoroborate → HCID 178498026, compound

HRID 2018071Notes

Reaction equation

HRID 2018071 reaction equation
[CH3:1][O:2][C:3]([c:5]1[c:11]([CH:12]([O:14][c:15]2[c:20]([NH2:21])[n:19][cH:18][c:17]([c:22]3[c:30]([CH2:31][N:32]([C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[CH3:33])[n:26]([CH2:27][C:28]#[N:29])[n:25][c:23]3[CH3:24])[n:16]2)[CH3:13])[c:10](Cl)[c:8]([F:9])[cH:7][cH:6]1)=[O:4].[K+].F[B-]([CH:41]1[CH2:43][CH2:42]1)(F)F>>[CH3:1][O:2][C:3]([c:5]1[c:11]([CH:12]([O:14][c:15]2[c:20]([NH2:21])[n:19][cH:18][c:17]([c:22]3[c:30]([CH2:31][N:32]([C:34]([O:36][C:37]([CH3:40])([CH3:39])[CH3:38])=[O:35])[CH3:33])[n:26]([CH2:27][C:28]#[N:29])[n:25][c:23]3[CH3:24])[n:16]2)[CH3:13])[c:10]([CH:41]4[CH2:43][CH2:42]4)[c:8]([F:9])[cH:7][cH:6]1)=[O:4]

Participants

8

Reactant 2

HCID 23697338Potassium cyclopropyltrifluoroborateHCID 178498029HCID 178498029, compound

Product 1

HCID 178498026HCID 178498026, compound

Reagents, catalysts & solvents 5

HCID 11430Potassium CarbonateReagentHCID 167845palladium(II) acetateCatalystHCID 178454858HCID 178454858, compoundCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-61c52de33b5543e384b9ab1481b877a4
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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