2,4,6-Trichloropyrimidine → HCID 65710860, compound

HRID 2018485Notes

Reaction equation

HRID 2018485 reaction equation
Cl[c:1]1[n:8][c:6]([Cl:7])[n:5][c:3]([Cl:4])[cH:2]1.[CH3:9][c:10]1[c:15](B2OC(C)(C)C(C)(C)O2)[cH:14][n:12]([CH3:13])[n:11]1>>[CH3:9][c:10]1[c:15]([c:1]2[n:8][c:6]([Cl:7])[n:5][c:3]([Cl:4])[cH:2]2)[cH:14][n:12]([CH3:13])[n:11]1

Participants

9

Reactant 2

HCID 773782,4,6-TrichloropyrimidineHCID 426473161,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Product 1

HCID 65710860HCID 65710860, compound

Reagents, catalysts & solvents 6

HCID 962WaterReagentHCID 516892Sodium BicarbonateReagentHCID 167845palladium(II) acetateCatalystHCID 178454858HCID 178454858, compoundCatalystHCID 6342AcetonitrileSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
60 °C

Sources & evidence

ORD record
ord-208a7871c4cb407c8bef3a595c244be2
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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