2-Bromopyridine → HCID 178480799, compound

HRID 2018505Notes

Reaction equation

HRID 2018505 reaction equation
Br[c:1]1[n:6][cH:5][cH:4][cH:3][cH:2]1.[CH3:7][N:8]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[C@H:9]1[CH2:12][C@H:11]([O:13][c:14]2[c:29]([c:25]3[n:24][c:16]([NH:17][c:18]4[cH:23][n:21]([CH3:22])[n:20][cH:19]4)[n:15]2)[cH:28][cH:27][nH:26]3)[CH2:10]1>>[CH3:7][N:8]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[C@H:9]1[CH2:12][C@H:11]([O:13][c:14]2[c:29]([c:25]3[n:24][c:16]([NH:17][c:18]4[cH:23][n:21]([CH3:22])[n:20][cH:19]4)[n:15]2)[c:28]([c:1]5[n:6][cH:5][cH:4][cH:3][cH:2]5)[cH:27][nH:26]3)[CH2:10]1

Participants

8

Reactant 2

HCID 79732-BromopyridineHCID 178480802HCID 178480802, compound

Product 1

HCID 178480799HCID 178480799, compound

Reagents, catalysts & solvents 5

HCID 517045Sodium AcetateReagentHCID 167845palladium(II) acetateCatalystHCID 178492614HCID 178492614, compoundCatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
90 °C

Sources & evidence

ORD record
ord-ea57fc8832aa477e9751d9fab71c49d5
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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