5-broMo-1,4-diMethyl-1H-iMidazole → HCID 178425079, compound

HRID 2018686Notes

Reaction equation

HRID 2018686 reaction equation
[CH3:1][c:2]1[n:29][c:20]([O:21][CH2:22][c:23]2[cH:28][cH:27][cH:26][cH:25][cH:24]2)[c:6]([CH2:7][N:8]3[C:18](=[O:19])[c:17]([c:11]4[CH2:10][CH2:9]3)[c:15]([Cl:16])[c:14]([Sn](C)(C)C)[cH:13][cH:12]4)[c:4]([CH3:5])[cH:3]1.[CH3:30][c:31]1[c:36](Br)[n:34]([CH3:35])[cH:33][n:32]1>>[CH3:1][c:2]1[n:29][c:20]([O:21][CH2:22][c:23]2[cH:28][cH:27][cH:26][cH:25][cH:24]2)[c:6]([CH2:7][N:8]3[C:18](=[O:19])[c:17]([c:11]4[CH2:10][CH2:9]3)[c:15]([Cl:16])[c:14]([c:36]5[n:34]([CH3:35])[cH:33][n:32][c:31]5[CH3:30])[cH:13][cH:12]4)[c:4]([CH3:5])[cH:3]1

Participants

9

Reactant 2

HCID 586418315-broMo-1,4-diMethyl-1H-iMidazoleHCID 178425083HCID 178425083, compound

Product 1

HCID 178425079HCID 178425079, compound

Reagents, catalysts & solvents 6

HCID 62652Cuprous chlorideReagentHCID 433294Lithium ChlorideReagentHCID 11979704Tetrakis(triphenylphosphine)palladiumCatalystHCID 962WaterSolventHCID 31374DimethylacetamideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-01c99d0f7fdb432bb79cf2c3a4f169bf
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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