Bromobenzene → HCID 871639, compound

HRID 2018695Notes

Reaction equation

HRID 2018695 reaction equation
[CH3:1][S:2]([N:5]1[CH2:10][CH2:9][N:8]([c:11]2[cH:16][cH:15][cH:14][cH:13][cH:12]2)[CH2:7][CH2:6]1)(=[O:4])=[O:3].Br[c:17]1[cH:22][cH:21][cH:20][cH:19][cH:18]1>>[O:3]=[S:2]([N:5]1[CH2:10][CH2:9][N:8]([c:11]2[cH:16][cH:15][cH:14][cH:13][cH:12]2)[CH2:7][CH2:6]1)([CH2:1][c:17]3[cH:22][cH:21][cH:20][cH:19][cH:18]3)=[O:4]

Participants

8

Reactant 2

HCID 7961BromobenzeneHCID 7990161-methylsulfonyl-4-phenylpiperazine

Product 1

HCID 871639HCID 871639, compound

Reagents, catalysts & solvents 5

HCID 3251421Potassium bis(trimethylsilyl)amideReagentHCID 167845palladium(II) acetateCatalystHCID 155884980(R)-(-)-1-[(S)-2-(dicyclohexylphosphino)ferrocenyl]ethyldicyclohexylphosphineCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-4857659b9deb4fefaba4eff0ad5c0aba
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…