Bromobenzene → HCID 871639, compound

HRID 2018696Notes

Reaction equation

HRID 2018696 reaction equation
Br[c:1]1[cH:6][cH:5][cH:4][cH:3][cH:2]1.[CH3:7][S:8]([N:11]1[CH2:16][CH2:15][N:14]([c:17]2[cH:22][cH:21][cH:20][cH:19][cH:18]2)[CH2:13][CH2:12]1)(=[O:10])=[O:9]>>[O:9]=[S:8]([N:11]1[CH2:16][CH2:15][N:14]([c:17]2[cH:22][cH:21][cH:20][cH:19][cH:18]2)[CH2:13][CH2:12]1)([CH2:7][c:1]3[cH:6][cH:5][cH:4][cH:3][cH:2]3)=[O:10]

Participants

8

Reactant 2

HCID 7961BromobenzeneHCID 7990161-methylsulfonyl-4-phenylpiperazine

Product 1

HCID 871639HCID 871639, compound

Reagents, catalysts & solvents 5

HCID 3251421Potassium bis(trimethylsilyl)amideReagentHCID 167845palladium(II) acetateCatalystHCID 117064351(R)-1-[(S)-2-(Dicyclohexylphosphino)ferrocenyl]ethyli-tert-butylphosphineCatalystHCID 1140TolueneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-adedb934c74148ca9145abf28ed87129
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

Loading…