HCID 118663246, compound → HCID 137646576, compound

HRID 2021156Notes

Reaction equation

HRID 2021156 reaction equation
[CH3:1][c:2]1[n:6][c:5]([c:7]2[cH:13][cH:12][c:10]([CH2:11]Cl)[cH:9][cH:8]2)[cH:4][o:3]1.[CH3:14][c:15]1[c:32](B2OC(C)(C)C(C)(C)O2)[cH:31][c:30]([c:17]3[cH:16]1)[C:28](=[O:29])[N:20]([C@@H:21]4[C@@H:26]([OH:27])[CH2:25][O:24][CH2:23][CH2:22]4)[CH2:19][CH2:18]3>>[CH3:1][c:2]1[n:6][c:5]([c:7]2[cH:13][cH:12][c:10]([CH2:11][c:32]3[c:15]([CH3:14])[cH:16][c:17]([c:30]4[cH:31]3)[CH2:18][CH2:19][N:20]([C@@H:21]5[C@@H:26]([OH:27])[CH2:25][O:24][CH2:23][CH2:22]5)[C:28]4=[O:29])[cH:9][cH:8]2)[cH:4][o:3]1

Participants

9

Reactant 2

HCID 118663246HCID 118663246, compoundHCID 178421824HCID 178421824, compound

Product 1

HCID 137646576HCID 137646576, compound

Reagents, catalysts & solvents 6

HCID 962WaterReagentHCID 25953Cesium fluorideReagentHCID 167845palladium(II) acetateCatalystHCID 111557942-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenylCatalystHCID 887MethanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-800a69dceb3f4548a53968a4a114fe7e
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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