Acetylene → 4-Chloro-1,7-naphthyridin-8(7H)-one
Reaction equation
CO[NH:1][C:2]([c:4]1[n:10][cH:9][cH:8][c:6]([Cl:7])[cH:5]1)=[O:3].[CH:11]#[CH:12]>>[Cl:7][c:6]1[c:5]([c:4]2[n:10][cH:9][cH:8]1)[CH:12]=[CH:11][NH:1][C:2]2=[O:3]Participants
8
Reactant 2
Product 1
Reagents, catalysts & solvents 5
Conditions
- Temperature
- 60 °C
Sources & evidence
- ORD record
- ord-2b344d064b6f4056a48bfc039a40cf00
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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