4-Bromo-5-fluoro-2-methylbenzaldehyde → 4-Bromo-5-fluoro-2-methylbenzaldehyde

HRID 2026452Notes

Reaction equation

HRID 2026452 reaction equation
[CH3:1][c:2]1[c:9]([CH:10]=[O:11])[cH:8][c:6]([F:7])[c:4]([Br:5])[cH:3]1.[Cu]C#N>>[CH3:1][c:2]1[c:9]([CH:10]=[O:11])[cH:8][c:6]([F:7])[c:4]([Br:5])[cH:3]1

Participants

7

Reactant 2

HCID 121872174-Bromo-5-fluoro-2-methylbenzaldehydeHCID 178418546HCID 178418546, compound

Product 1

HCID 121872174-Bromo-5-fluoro-2-methylbenzaldehyde

Reagents, catalysts & solvents 4

HCID 80271Tri-o-tolylphosphineCatalystHCID 167845palladium(II) acetateCatalystHCID 312751,4-DioxaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-b61e5b14b2fd4fb3af861a080ca55dab
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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