3,5-Dibromo-4-methylpyridine → 5-Bromo-4-methylpyridine-3-carbonitrile

HRID 2030987Notes

Reaction equation

HRID 2030987 reaction equation
[OH-].CCC[CH2:1][N+:2](CCCC)(CCCC)CCCC.[CH3:3][c:4]1[c:10](Br)[cH:9][n:8][cH:7][c:5]1[Br:6]>>[CH3:3][c:4]1[c:10]([C:1]#[N:2])[cH:9][n:8][cH:7][c:5]1[Br:6]

Participants

5

Reactant 2

HCID 8193383,5-Dibromo-4-methylpyridineHCID 2723671Tetrabutylammonium Hydroxide

Product 1

HCID 70606815-Bromo-4-methylpyridine-3-carbonitrile

Reagents, catalysts & solvents 2

HCID 31374DimethylacetamideSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
120 °C

Sources & evidence

ORD record
ord-f7cacd78fe1d4a1b9506ee4d10d52a73
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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