3,5-Dibromo-4-methylpyridine → 5-Bromo-4-methylpyridine-3-carbonitrile
Reaction equation
[CH3:1][Si]([N:2]([Si](C)(C)C)[Na])(C)C.[CH3:3][c:4]1[c:10](Br)[cH:9][n:8][cH:7][c:5]1[Br:6]>>[CH3:3][c:4]1[c:10]([C:1]#[N:2])[cH:9][n:8][cH:7][c:5]1[Br:6]Participants
6
Reactant 2
Product 1
Reagents, catalysts & solvents 3
Conditions
- Temperature
- 120 °C
Sources & evidence
- ORD record
- ord-0d22961f4c5c4f6581f069b45c3240f7
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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