Water → HCID 89807582, compound

HRID 2033932Notes

Reaction equation

HRID 2033932 reaction equation
O.[CH3:1][C@H:2]([c:11]1[c:17]([C:18]([N:20]([CH2:22][c:23]2[n:32][n:31][n:25]([CH2:26][CH:27]3[CH2:30][CH2:29][CH2:28]3)[cH:24]2)[CH3:21])=[O:19])[cH:16][cH:15][c:13]([F:14])[cH:12]1)[O:3][c:4]4[c:9]([NH2:10])[n:8][cH:7][c:6](Br)[cH:5]4>>[CH3:1][C@@H:2]1[c:11]([c:17]2[C:18](=[O:19])[N:20]([CH3:21])[CH2:22][c:23]3[c:24]([n:25]([CH2:26][CH:27]4[CH2:30][CH2:29][CH2:28]4)[n:31][n:32]3)[c:6]5[cH:5][c:4]([c:9]([NH2:10])[n:8][cH:7]5)[O:3]1)[cH:12][c:13]([F:14])[cH:15][cH:16]2

Participants

8

Reactant 2

HCID 962WaterHCID 178462221HCID 178462221, compound

Product 1

HCID 89807582HCID 89807582, compound

Reagents, catalysts & solvents 5

HCID 517044Potassium AcetateReagentHCID 167845palladium(II) acetateCatalystHCID 178454858HCID 178454858, compoundCatalystHCID 64052-Methyl-2-butanolSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
110 °C

Sources & evidence

ORD record
ord-02fc48f86a4945c4a8c91c83b093f671
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Reaction notes

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